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Detecting the Invisible: New Technique Reveals Earliest Signs of Genetic Mutations

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Detecting the Invisible: New Technique Reveals Earliest Signs of Genetic Mutations

HiDEF-seq, a groundbreaking technique from NYU Langone Health, identifies early DNA changes that precede mutations, enhancing understanding of genetic disorders and aging. Mutations are alterations in the molecular “letters” that compose the DNA code, which serves as the blueprint for all living cells. While some of these changes have minimal impact…
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Après l’exploit, le retour sur terre : Monfils renversé par Rune

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Après l’exploit, le retour sur terre : Monfils renversé par Rune

La folle journée de Gaël Monfils su0027est achevée sur une défaite. Le Français, vainqueur de Carlos Alcaraz un peu plus tôt pour ce qui était un sacré exploit, a été battu par Holger Rune en huitième de finale dans la nuit de vendredi à samedi. Le Français avait pourtant pris le premier set en surfant sur sa confiance…
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Now, Sir! Donald Trump Calls Out Barack And Michelle Obama For Taking “Personal” Jabs At The DNC (VIDEO)

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Now, Sir! Donald Trump Calls Out Barack And Michelle Obama For Taking “Personal” Jabs At The DNC (VIDEO)

After their Democratic National Convention (DNC) speeches, Barack and Michelle Obama were met with loud cheers and applause. Meanwhile, Donald Trump was somewhat less pleased and impressed with Michelle and Obama! On Wednesday (August 21), he took a lil’ moment during a rally to call out the Obamas for getting “personal.”

RELATED: Here’s What’s Goin’ Down At The Democratic National Convention

Donald Trump Said THIS About Barack & Michelle Obama’s Speeches

According to Politico, Donald got his lick back at Obama and Michelle while speaking to a crowd in Asheboro, North Carolina.

“Did you see Barack Hussein Obama last night taking little shots? He was taking shots at your president, and so was Michelle,” Donald said. “You know, they always say, ‘Sir, please stick to policy, don’t get personal,’ but they’re getting personal all night, these people.”

He later asked the crowd whether he, too, should “get personal” or “not get personal.” His rally audience voted for personal, highlighting a trend of Donald going for his opponent’s jugular.

President Joe Biden even caught some smoke on Wednesday from Trump, who called out the president’s recent “bathing suit” vacation photos.

RELATED: Get It Joe! See President Biden Catch A Self-Care Vibe At Delaware Beach (PHOTOS)

Here’s What The Obamas Said On The 2024 DNC Stage

As mentioned, the Obamas shared powerful words in their hometown, Chicago, about leadership and their faith in Vice President Kamala Harris’ vision for America.

Moreover, the former president and First Lady seemingly abandoned Michelle’s 2016 mantra of going high when others go low! In fact, Michelle slammed Donnie for using the “same old con” and behaving “unpresidential.”

“Going small is petty, it’s unhealthy, and, quite frankly, it’s unpresidential,” Michelle reportedly stated, per Politico. “It’s his same old con: doubling down on ugly, misogynistic, racist lies as a substitute for real ideas and solutions that will actually make people’s lives better.”

Elsewhere in her speech, she aimed his previous viral comment about “Black jobs.” For context, he made the comment during his first presidential debate against former candidate President Joe Biden in June.

“Who’s gonna tell him that the job he’s currently seeking might just be one of those Black jobs,” Michelle stated, riling up the crowd!

Meanwhile, Barack touched on a few other sore spots for Donald that Michelle didn’t! “There’s the childish nicknames, the crazy conspiracy theories, this weird obsession with crowd sizes,” Obama stated, picking at two sore spots for Donald: crowd sizes and being called “weird.”

Additionally, Mr. Obama passionately suggested that a “sequel” of Trump would be “worse.”

“We do not need four more years of bluster and bumbling and chaos. We have seen that movie before, and we all know that the sequel is usually worse. America is ready for a new chapter; America is ready for a better story. We are ready for a President Kamala Harris and Kamala Harris is ready for the job.”

Beyoncé’s Camp Reportedly Threatens Trump With Cease-And-Desist Over Use Of ‘Freedom’

While Donnie spent time coming for the Obamas, Beyoncé and her team of lawyers might be coming for him!

According to Rolling Stone, a source has revealed that Bey threatened the GOP presidential candidate with a lawsuit after he shared a 13-second clip featuring her song ‘Freedom.’ The video campaign spokesperson Steven Cheung shared on X reportedly showed Donald stepping off a plane in Michigan.

For context, the song is an unofficial part of Kamala Harris’ campaign run. But Harris appears to have the necessary clearance that Donald’s camp doesn’t!

Rolling Stone reports that unauthorized use of music has been a norm in Trump’s campaign, with “dozens” of musicians expressing pushback and threatening legal action. Most recently, that list includes the family of Issac Hayes.

RELATED: Aht Aht! The Family Of Late Singer Isaac Hayes Threatens To Sue Donald Trump

What Do You Think Roomies?

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How far has mpox spread and how can you protect yourself?

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How far has mpox spread and how can you protect yourself?

At least two countries outside of Africa have reported mpox cases after the World Health Organization (WHO) declared that the virus had become a “public health emergency” earlier this week.

A relatively new strain of the virus known as clade 1 has been spreading in African countries since 2022.

Earlier this year, it was reported that the Democratic Republic of Congo (DRC) was experiencing the biggest outbreak of the disease ever recorded, with tens of thousands of people infected as of June. The government of DRC had declared it an epidemic in December 2022.

Last week, the Africa CDC reported that mpox has now been detected in at least 13 African countries. Compared with the same period last year, the agency said cases are up 160 percent and deaths have increased by 19 percent.

Here is what we know so far about where the disease has spread, how it affects the human body and how to protect yourself from infection.

To which other countries has the new strain of mpox virus spread?

The Pakistan Ministry of National Health Services confirmed its first case of the virus on Friday, saying the person had come from Saudi Arabia.

Health officials said sequencing is underway to determine the exact strain of the virus the person had been infected with.

On Thursday, Swedish health officials reported the country’s first case of mpox, confirming that it was the clade 1 strain, and said the person had become infected in Africa and is now receiving treatment.

Clade 1 tends to cause a higher number of severe infections and appears to be more easily spread through routine close contact, including sexual contact.

On Friday, the European Center for Disease Prevention and Control (CDC) raised its risk alert level to “moderate” from “low” and asked countries to maintain high levels of awareness among travellers visiting from affected areas.

How does the virus attack the human body?

Mpox mainly affects humans and animals. It belongs to the same family of viruses as smallpox but causes milder symptoms, such as fever, chills, and body aches. It can cause severe illness, and even death in some cases, however.

The virus enters the human body through broken skin or via the airways. It then spreads through the blood causing a person to experience flu-like symptoms and develop lesions on the skin.

According to Michael Marks at the London School of Hygiene and Tropical Medicine, scientists “don’t think that mpox has direct effects on the immune system”.

“Beyond the fact that all infections obviously transiently cause responses in the immune system, we don’t believe there are long-term impacts on the immune system from mpox,” he said.

Dr Ngashi Ngongo, chief of staff at Africa CDC, also told Al Jazeera that the virus only causes symptoms that last “two to four weeks”.

“It’s a disease. Whether you get the severe form – then it leads to death – or you just recover [in] two to four weeks. Everything goes back to normal,” he said.

How does the virus spread?

The virus is spread by close contact with an infected person or animal. For human-to-human infection, the virus can be passed on through contact with skin lesions, skin-to-skin contact, and talking or breathing too close to an infected person.

It can also be spread via contaminated objects such as surfaces, bedding, clothing and towels, as the virus enters the body through broken skin, the respiratory tract, or the eyes, nose, and mouth.

Marks told Al Jazeera that the most important form of transmission is through skin-to-skin contact as the virus remains detectable on skin lesions for “three weeks or so”, rather than via the respiratory system since in “most people the virus is cleared from the throat by seven to 10 days”.

For human-to-animal transmission, the virus typically enters the body through bites, scratches or contact with the wounds on an infected animal.

INTERACTIVE- How does monkeypox spread infographic-1723724440

What are the symptoms?

The disease causes flu-like symptoms and pus-filled lesions. It is usually mild but can be severe enough to kill.

Marks explained that most people have a “relatively mild illness” where they could have a fever, muscle aches and a rash with “five to 25 lesions”.

“Some people become much more unwell and they may develop a more severe illness with hundreds of lesions all over the body,” he said.

What variables can cause more severe symptoms?

While Marks explained that the illness presents mild symptoms in most people, some people are at higher risk of experiencing severe symptoms.

“For example, people with untreated HIV [a sexually transmitted illness] or a weak immune system are at still higher risk of severe disease. Children also seem to be at higher risk of severe disease,” he said.

Children, he explained, are likely affected by mpox more than adults for “several reasons”.

“A lot of the transmission is in densely populated areas with many children, and children are probably more prone to running around and coming into direct skin-to-skin contact with others – so that then causes transmission. Whereas adults have less direct contact with others,” he said.

Ngongo added that children are also at higher risk as their “defence mechanism” – the immune system – is still developing.

What treatment is available for this strain of mpox?

There is no current treatment for mpox but some antiviral drugs are being tested, Marks said.

“There is, however, vaccination, which is effective at reducing risk. The priority needs to be getting an adequate supply of vaccine to those populations most at risk in DRC and surrounding countries,” he said.

“If we can vaccinate individuals at risk they will be protected from infection and this will help control the epidemic – so both benefit the person vaccinated and the broader population,” he added.

A vaccine for mpox, which was used in the 2022 outbreak by many Western countries, is not accessible by poorer African nations, Ngongo explained.

“There is no vaccine in Africa. Whatever is left of that vaccine is stockpiled in the West as part of their own emergency preparedness. But we have an ongoing emergency here,” he said.

Ngongo explained that through donations, Africa CDC has managed to obtain 280,000 doses. However, for the vaccine to be effective, people must take two doses, lowering the amount they have for 140,000 people only.

How can you protect yourself?

Ngongo advised people to “go back to the basics of personal hygiene” and remember to wash hands, avoid contact with those who are sick and advise people to go to the hospital if they are displaying symptoms so that the virus can be contained.

Mpox vaccines are also effective in protecting the population if you are in a country where it is accessible.

Could the mpox virus spread further?

Given the resources in richer countries to stop the spread of the virus, scientists believe that if new outbreaks linked to Congo are identified quickly, transmissions could be stopped relatively quickly.

The “major risk”, Marks said, is in central Africa where the epidemic is occurring and spreading.

“There are likely to be small numbers of cases exported further afield, as [in] the Swedish case, but the major risk and the focus for action needs to be on central Africa,” he said.

Ngongo also urged people to learn from the COVID-19 pandemic and “act now”.

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‘We’re not going back’: Walz pushes back against Trump and Project 2025

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‘We’re not going back’: Walz pushes back against Trump and Project 2025

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Donald Trump praises ‘warrior’ Dustin Poirier for performance against Islam Makhachev: “He didn’t lose that fight”

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Donald Trump praises ‘warrior’ Dustin Poirier for performance against Islam Makhachev: “He didn’t lose that fight”

Former U.S. President Donald Trump has nothing but praise for UFC lightweight Dustin Poirier.

‘The Diamond’ is fresh off his return to the cage earlier this summer at UFC 302. In the main event of that pay-per-view card, Dustin Poirier faced lightweight champion Islam Makhachev. Entering the contest, the longtime fan favorite was a massive underdog. However, Poirier admitted that the bout could be his last and that he was willing to go out on his shield.

Ultimately, the former interim champion gave a herculean effort in June. However, Dustin Poirier wound up being submitted in the fifth round, after a surprising amount of success. Post-fight, the lightweight contender stated that he may retire, but has since u-turned on those plans. If there’s one man excited to see him back, it’s Donald Trump.

The 45th U.S. President and Republican nominee is a noted UFC fan. While Donald Trump has gone on record stating that Khabib Nurmagomedov is his favorite fighter of all time, he still has massive respect for Dustin Poirier. In a recent interview with comedian Theo Von, the politician reacted to ‘The Diamond” losing to Islam Makhachev.

RELATED: CHARLES OLIVEIRA INTERESTED IN FACING FORMER UFC FEATHERWEIGHT CHAMPION ALEXANDER VOLKANOVSKI NEXT: “WHY NOT?”

Donald Trump praises “warrior” Dustin Poirier and talks about his fight with Islam Makhachev:

“He didn’t lose that fight… As that fight went along he just got stronger and stronger.

He was getting pounded, and he was going to be choked out about four different times and he… pic.twitter.com/acOGQmGdEQ

— Championship Rounds (@ChampRDS) August 21, 2024

Donald Trump praises Dustin Poirier for UFC 302 performance against Islam Makhachev

There, the Presidential candidate was full of praise for Dustin Poirier. Donald Trump stated that the UFC lightweight contender had a lot of moral victories in his loss to Makhachev. While Poirier left the cage with a submission loss, the politician couldn’t help but be impressed by his heart.

“Oh he’s great, boy I’ll tell you he’s a warrior.” Donald Trump stated when asked about Dustin Poirier. “Whether you like him or not, he’s a warrior. No, he didn’t lose that fight. He really, man, his fight was tough. He was tough and I didn’t expect that same fight. [Poirier] makes people suffer, there’s no question about that. He’s a pro, he’s a professional.”

He continued, “As that fight went along, he just got stronger and stronger. He was getting pounded and was going to be choked out four different times and he just wouldn’t let it happen. Man, he’s good, he’s a really great fighter.”

What do you make of these comments about UFC lightweight contender Dustin Poirier? Do you agree with Donald Trump?

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Maybank branch in Kota Kinabalu becomes popular attraction among China tourists, Malaysia News

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Maybank branch in Kota Kinabalu becomes popular attraction among China tourists, Malaysia News

What is a unique attraction to photograph while travelling in Malaysia, one that will always bring the trip to mind? The answer, at least when visiting Kota Kinabalu (KK) in the state of Sabah, seems to be a bank. The Maybank branch on KK’s Gaya Street has become Sabah’s latest scenic spot to photograph, alongside
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EU urged to issue travel warnings as Mpox risk in Africa grows

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EU urged to issue travel warnings as Mpox risk in Africa grows

Since last year, mpox has been spreading in the DRC and other African countries, causing over 500 deaths, mostly in the DRC…
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MSG Entertainment Has Been a Spun-Off Standalone Public Company for One Year — Here’s How It’s Faring Financially

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MSG Entertainment Has Been a Spun-Off Standalone Public Company for One Year — Here’s How It’s Faring Financially

Madison Square Garden Entertainment celebrates one year as a standalone public company with revenues over 26% higher this quarter. Madison Square Garden Entertainment (MSGE) has been a standalone public company for a year now, and its recently posted quarterly financials show just how well the company is doing financially…
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Ten Hag must dodge Manchester United sack for month to avoid place among ten earliest exits

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Ten Hag must dodge Manchester United sack for month to avoid place among ten earliest exits

The new Premier League season is nearly upon us, and that means we’re just days away from some poor sod or other facing kneejerk reactions that they need to be sacked – just like this little lot here. We’re going by days after the season began…
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